(Hemoglobin is a protein thats found in your red blood cells.). And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Terminal half-life ranges from 7 to 12 hours. People in the study received treatment with either Injectafer or Venofer. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. But keep in mind that in this study, delayed allergic reaction only occurred in one person. These side effects may include constipation and diarrhea. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Injectafer contains the active drug ferric carboxymaltose. Health careproviderscan provide information on how longside effectslast by checking amedication guide. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. If you notice any changes to your normal blood pressure, call your doctor right away. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Vomiting. (For more information on Venofer, see the Injectafer vs. Venofer section above). Most people will metabolize medication by half every time it circulates the body. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. Side effects from HRT depend on a number of factors: If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Back pain. Talk with the doctor. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Before using, check this product visually for particles or discoloration. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. The iron released by this drug does pass into human breast milk. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. WebMD provides common contraindications for Venofer Vial. These effects typically last between 7 and 11 hours. Version: 7.01. Upset stomach or throwing up. Injectafer begins working as soon as it enters your body. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. endobj Side effects like nausea and low blood pressure are common with most iron infusions. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Here are answers to some frequently asked questions about Injectafer. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. But if they become more severe or dont go away, talk with your doctor or pharmacist. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. Its responsible for carrying oxygen throughout your body. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. For example: Say you weigh 105 pounds (about 48 kilograms). Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. wAd**CgI%"nn{Oa[q{r5 With anemia, you have a low level of red blood cells (RBCs) in your body. There are currently no generic forms of either drug. Drug class: Iron products. upper respiratory infection. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. The study also didnt show if one treatment was worse than the other. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. And this person had gotten their first dose of the drug without having an allergic reaction. 3 0 obj Last reviewed . I can't take oral supplements because they cause horrible debilitating Constipation. <> During Injectafer treatment, your doctor will likely order blood tests. Heart failure: Could a low sodium diet sometimes do more harm than good? Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. experience severe side effects, please seek medical attention right away and notify the ordering physician. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. (A generic drug is an exact copy of the active drug in a brand-name medication.) Keep all medications away from children and pets. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Can diet help improve depression symptoms? It belongs to a class of medications called iron replacement products. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Together, you and your doctor can develop a treatment plan thats best for you. However, diarrhea it isnt very common in people using Injectafer. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. Review our medical disclaimer. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Headache. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Do not flush down a toilet or pour down a drain unless you are told to do so. This test measures the amount of hemoglobin in your blood. Side effectsare uncomfortable reactions to medications or drugs. Iron infusion side effects vary depending on which form is being used. A variety of tests can diagnose iron deficiency anemia. Cardiovascular health: Insomnia linked to greater risk of heart attack. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Be ready to tell or show what was taken, how much, and when it happened. However, many people have no side effects or only have minor side effects. The drug helps increase your hemoglobin level back to a value thats within the normal range. If you think there has been an overdose, call your poison control center or get medical care right away. Remember that it is best to get your vitamins and minerals from food whenever possible. Injectafer should be stored between 68F to 77F (20C to 25C). People from different ethnic backgrounds process medications differently. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Injectafer and Feraheme are both brand-name drugs. Your doctor will go over your Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Venofer pregnancy and breastfeeding warnings. (See also Notes section.). Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Venofer is for use in adults and children at least 2 years old. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. Its not known if Injectafer is safe to take during pregnancy. This can be very helpful in . On the other hand, some people may have a poor appetite that goes away when their anemia is treated. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. But for other people, their anemia may come back after Injectafer treatment. Feraheme also comes as a liquid thats given by IV infusion. There have also been reports of serious allergic reactions to Venofer. Do not exceed 1,500 mg of iron per dosing course. They have been a god send. endobj I used to get a different type but my . Iron sucrose can also be mixed in a. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. If you notice other effects not listed above, contact your doctor or pharmacist. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Follow your doctor's directions carefully. Consult your doctor before breast-feeding. These people may lose weight as their anemia improves because theyre more active. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Have blood work checked as you have been told by the doctor. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Allergic reactions typically occur the first time your body is exposed to a drug. All of the people took iron by mouth for 2 weeks. Iron infusion benefits. The information provided is not intended to replace your healthcare provider's medical advice. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). These pregnancy-related problems include preterm delivery and low birth weight of your infant.